A live-cell biosensor of in vivo receptor tyrosine kinase activity reveals feedback regulation of a developmental gradient.

Author

EK Ho, Rebecca Kim-Yip, Alison Simpkins, Payam Farahani, Harrison Oatman, Eszter Posfai, Stanislav Shvartsman, Jared Toettcher

Publication Year

2025

Type

Journal Article

Keywords

CP: Cell Biology, CP: Developmental biology, Drosophila development, ERK signaling, biosensor, receptor tyrosine kinases

Journal

Cell reports

Volume

44

Issue

7

Pages

115930

Date Published

06/2025

ISSN Number

2211-1247

URL

External link to reference

DOI

10.1016/j.celrep.2025.115930

Alternate Journal

Cell Rep

PMID

40581929